Insider analyzed more than 90 IPOs to find the top venture-capital firms that led biotech in 2021. Flagship, based in Cambridge, Massachusetts, is more of a venture-creation firm than a traditional VC it often creates the companies it invests in. WebThe 45 most important VCs in Texas, according to other VCs. The curated list of the most valuable private companies in the world |. Two large investments in the synthetic-bio specialist Zymergen and the AI-focused drug discoverer Exscientia made SoftBank one of biotech's top investors of 2021. No money was reported to have been raised, and a size was not disclosed for the fund. With a strong M&A environment for exits, venture capitalists continue to fuel biotech industry growth. These VC firms led the most funding rounds for biotech startups this year between Jan. 1 and Dec. 1, according to Crunchbase data. 9 See announcement on the firms blog, http://indexventures.com/news-room/blog/our-new-fund-for-building-iconic-businesses Insights about top trending companies, startups, investments and M&A activities, notable investors of these companies, their management team, and recent Below is this years GEN list of 20 top venture capital firms, and broader financial firms that invest venture capital or other equity in early- to late-stage biotechnology and pharmaceutical companies, ranked by total capital under management or, for some firms, total active committed capital from funds in use. Top Cities Offering Biotech Jobs 1. Since then, the company has raised seven more funds, totaling over $2.5 billion, making it one of the worlds largest and most renowned Biosciences venture capital companies. The firm prefers to invest in companies from the software, blockchain, robotics, software-as-a-service, artificial intelligence, and machine learning sectors. (12), Current fund: 250 million ($310 million) Highland Capital Growth Fund, closed in May; and the $400 million Highland Capital Partners IX L.P., closed 2013. Reporting by Sohini Podder and Noor Zainab Hussain in Bengaluru; Editing by Maju Samuel. With $19 billion in assets under management, OrbiMed is set to be a leader next year as well. Since launching its healthcare technology investments in 1993, the group has become one of the industrys top venture capitalists. The firm is headquartered in San Francisco, California. Venture capital in U.S. and Europe biotechnology industry 2015-2021 U.S. bioscience venture capital investments by segment 2018-2021 biotechnology funding by National Institutes for Health 2013-2023 Partners & Co-Founders Brad Bentz, Danielle Weiss Allen and Chris Shonk. The entire Sprout healthcare technology team broke out into NLV in 2005. Another six venture firms disclosed plans to raise new funds totaling an additional reported $2.78 billion; the actual number is undoubtedly higher, since one of those firms would not disclose a figure on its Form D. So who else joined those firms in investing capital in biotechs this year? Business Products and Services (B2B), Consumer Products and Services (B2C), Financial Services, Information Technology, Materials and Resources. As a spin-off of the Sprout Group, NLVP has been participating in Biopharma since 2005. Additionally, Bain Capital Crypto closed a $500 million fund in March 2022, and the firm announced a $2.4 billion Tech Opportunities fund earlier this month. Fund size and status: More than $14 billion in committed capital across 14 funds, Current fund: $2.6 billion New Enterprise Associates 14 L.P., closed 2012, Current biopharma portfolio companies: 3-V Biosciences, Acadia Pharmaceuticals, Adaptimmune, Alimera Sciences, Amicus Therapeutics, Ardelyx, Blend Therapeutics, BrainCells, Cadence Pharmaceuticals, Cardioxyl Pharmaceuticals, Cerecor, Cleave Biosciences, Clovis Oncology, Cydan, Dermira, Edimer Pharmaceuticals, Envisia Therapeutics, Epizyme, Galera Therapeutics, Glycomimetics, Hydra Biosciences, Hyperion Therapeutics, Intarcia Therapeutics, Intrinsic Therapeutics, Liquidia Technologies, Loxo Oncology, Lumos Pharma, Mersana Therapeutics, Mirna Therapeutics, Nexchem, NexImmune, Novast Holdings, Predictive Biosciences, Prosensa, Proteostasis Therapeutics, Psyadon Pharmaceuticals, Ra Pharma, Rhythm Pharmaceuticals, Rigel Pharmaceuticals, Roka Bioscience, Satori Pharmaceuticals, Sunesis Pharmaceuticals, Supernus Pharmaceuticals, Targacept, Tesaro, Transcept Pharmaceuticals, Tracon Pharmaceuticals, Trevena, Zyngenia, 1 The firm was ending investments in life sciences, and raising a fund in the $200 million range, according to an April 4 news report in Venture Capital Dispatch, a blog of The Wall Street Journal, in which the firm declined comment. To date, over 70 of the companys life science products have received FDA approval. Largest investment: 7.9 million shares of Vor Biopharma worth $142 million at the time of its IPO, Total holding value of 2021 IPOs: $1.3 billion. Although the two firms emerged as leaders in the data, they still make up a small part of the more than $120 billion in venture capital funds globally that poured into health and biotech startups as of Dec. 1 this year, Crunchbase data shows. In 2021, the health and biotech industry was second to only Fintech by VC investment raised. Several firms have already raised new funds and laid out investment plans for next year. The firm seeks to accelerate companies in the software, media and technology sectors in Texas. Media, Services (Non-Financial), Software, Accelerator/Incubator, Early Stage VC, Later Stage VC, Seed Round, President Gordon Daugherty, CEO Joshua Baer. The mean amount raised per round reached $84.4m in the first quarter, more than double that seen in the same period in 2020, while the median more than tripled. Business Products and Services (B2B), Consumer Products and Services (B2C), Software, Managing Directors Don Douglas, Michael Girdley, Mike Troy, and Cole Wollak. Karuna parts ways with executive as it gears up for schizophrenia drug's high-profile launch. Amidst rising interest rates and the looming threat of recession, the once-hot IPO market has come to a grinding halt. City (cities) where offices are located: San Francisco, Fund size and status: $2 billion under management across eight funds, Current fund: $500 million Alta Partners VIII, a first stage-independent life sciences fund closed 2006, Current biopharma portfolio companies: 7TM Pharma, Ablynx, AcelRx Pharmaceuticals, Achaogen, Aegerion Pharmaceuticals, Aerie Pharmaceuticals, Aerovance, Alba Therapeutics, Allakos, Applied Genetic Technologies, Astex Pharmaceuticals, aTyr Pharma, Azelon Pharmaceuticals, Cara Therapeutics, Ceregene, Cerenis Therapeutics, ChemoCentryx, Chimerix, Corcept Therapeutics, CymaBay Therapeutics, Cytokinetics, DiscoveRx, Esperion Therapeutics, Excaliard Pharmaceuticals, Genedata, Immune Design, Intarcia Therapeutics, Kiadis Pharma, Kite Pharma, Lumena Pharmaceuticals, MacroGenics, Neothetics, Nereus Pharmaceuticals, Pathwork Diagnostics, Portola Pharmaceuticals, Proacta Therapeutics, Prolacta Bioscience, SARcode Bioscience, Scynexis, Silence Therapeutics, Sonexa Therapeutics, Sunesis Pharmaceuticals, Sutro Biopharma, Threshold Pharmaceuticals, Trevena, Veloxis Pharmaceuticals, ViroBay, VitrOmics, Zafgen, ZS Pharma, City (cities) where offices are located: Radford, VA; San Francisco; Palm Beach, FL, Fund size and status: More than $2 billion under management through nine affiliated investment funds, consisting of seven New River Management Funds and two regional funds, Current New River Management Funds: $120 million New River Management VII, closed 2012; $15 million Valleys Ventures, launched 2013 to invest in companies that intend to commence operations in, or are willing to relocate to an area within 100 miles of Montgomery, Roanoke or Botetourt counties of southwestern Virginia, Current biopharma portfolio companies: Agilis, AmpliPhi Biosciences, AveXis, Fibrocell Science, Halozyme Therapeutics, Intrexon, Oragenics, OvaScience, Soligenix, Synthetic Biologics, City (cities) where offices are located: Menlo Park, CA, Fund size and status: More than $2 billion under management in nine funds, Most recent fund: $670 million MDV IX fund, first closed 2007 at $580 million. Latest biotech merger sees aimless Adamis snapped up by DMK - FierceBiotech 4h ago See: http://finance.yahoo.com/news/lightstone-ventures-closes-first-fund-123257593.html Founded in 2005, GOOSE Capital is a venture capital firm based in Houston, Texas. The Legal 500; United States . Asia Pacific ; RA Capital led the companys $336 million Series C ahead of the companys August IPO, though the firm hadnt participated in the companys earlier funding rounds. Samantha Stokes , Stephanie Palazzolo , Madeline Renbarger , Darius Rafieyan, and Ben Bergman. Largest investment: 16.2 million shares of Graphite Bio worth $276 million at the time of its IPO, Total holding value of 2021 IPOs: $846 million. Being bicoastal, the company primarily invests in the US eastern seaboard but has an international presence. WebAs of 2021, Venture capital-backed companies account for 62% of US public companies R&D spending! The firm seeks to invest in the business products and services sectors. CEO: John Doerr (chairman), Brook Byers (founder). Added to this, a new administration in the United States and its policy proposals, taxes, immigration, trade policy, and other issues that directly affect both VC investors and companies will all be on the table next year, PitchBook said in its 2021 U.S. venture capital outlook report. The firm prefers to invest in the aerospace, defense, energy, healthcare, information technology, industrials, and manufacturing sectors in Texas. Early Stage VC, Later Stage VC, PE Growth/Expansion, Seed Round. Insider analyzed corporate filings to identify the venture-capital firms that shaped these biotechs and are positioned to build on their success in 2022. This list includes corporate venture capital firms. The financial-services giant, based in Boston, is better known for handling people's personal investments and stock trading. Founded in 2017, Active Capital is a venture capital firm based in San Antonio, Texas. The Indian startup/ VC ecosystem will truly come of age htmlbody height HTML body div Here's Fierce Biotech's look at the This report is informational only. When Third Rock Ventures was established in 2007, the prospect of turning scientific advancements into ground-breaking medications set public imaginations on fire. Our Standards: The Thomson Reuters Trust Principles. Healthtech and biotech has consistently been a top sector for the destination of venture capital in recent years. Largest investment: 26.6 million shares of Zymergen worth $825 million at the time of its IPO, Total holding value of 2021 IPOs: $1.1 billion. To learn more about these VC firms and their 2021 investments take a look at their Crunchbase profiles: RA Capital Management OrbiMed Northpond Ventures Temasek 3 The general partners of the Life Sciences team and Advanced Technology Ventures joined investors from both in 2012 to create a new firm, Lightstone Ventures. The firm seeks to invest in B2B SaaS companies. Angermayer, who is also a movie producer, is especially interested in trying to develop psychedelics into medicines, with investments in ATAI Life Sciences and Compass Pathways, both of which focus on mental health. The lead investor often acts as the liaison between the startups founder(s) and the other participating investors, or is implicitly trusted by other investors to find the best terms for everyone. Apeiron, Christian Angermayer's investment firm, is based in Malta and has $3.5 billion in assets under management. 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The New York-based OrbiMed Healthcare Fund Management has made various investments in the life sciences sector, including MedTech and Biopharma. The list is ordered starting with the companies who invested the most in biotechnology. Fierce Pharma. RA Capital Management and OrbiMed led the way in both total dollars invested and the number of venture capital funding rounds led in the biotech industry last yearthe only two firms to make it onto both lists. WebJan 9, 2023 08:00am. See: http://www.sec.gov/Archives/edgar/data/1611731/000161173114000001/xslFormDX01/primary_doc.xml. Octopus Ventures is a London and New York based venture capital firm, focused on backing unusually talented entrepreneurs. Who has the most invested in funding up-and-coming biotechs? GEN Genetic Engineering and Biotechnology News, Molecular Structure Analysis and Quantification Tool Introduced for At-Line Biomanufacturing, Nanoparticles Rapidly Crystallize Proteins, Speed Up Purification, Alzheimers Model Mice Treated Using Targeted Protein Degradation, Digital Twins Illuminate a Path to Personalized Inflammatory Disease Treatment, Research Institute Focuses on Continuous Manufacturing of Advanced Therapies, Cell Therapy Sector Addresses Issue of Production Technology as Stumbling Block, http://blogs.wsj.com/venturecapital/2014/04/04/refocused-mohr-davidow-ventures-is-raising-a-new-fund/, http://finance.yahoo.com/news/lightstone-ventures-closes-first-fund-123257593.html, http://www.sec.gov/Archives/edgar/data/1612343/000161234314000001/xslFormDX01/primary_doc.xml, https://www.sec.gov/Archives/edgar/data/1602264/000160226414000001/xslFormDX01/primary_doc.xml, http://www.sec.gov/Archives/edgar/data/1609495/000160949214000002/xslFormDX01/primary_doc.xml, http://fortune.com/2014/10/02/exclusive-atlas-venture-is-splitting-up/, http://myemail.constantcontact.com/Announcing-Fund-VII.html?soid=1106633098844&aid=84wvr4fxTTs, http://www.sec.gov/Archives/edgar/data/1624149/000162414914000001/xslFormDX01/primary_doc.xml, http://www.sec.gov/Archives/edgar/data/1611731/000161173114000001/xslFormDX01/primary_doc.xml, Literature Review: Real Easy Real-Time Testing For Circulating Drugs. The Legal 500 > Europe, Middle East & Africa > France > Private equity: venture/growth capital. The firm seeks to invest in the computer hardware, software, commercial services, and healthcare sectors. VC firms only invest in companies that have long-term growth potential of at least 10X their investment, and that already have considerable traction (very fast revenue The company is steadily growing its life science footprint, emphasizing infrastructure, financial instruments, and real estate. While health and biotech are often almost inextricably linked, its worth noting that of that investment, a significant portion is heading directly to companies that place themselves specifically in the biotechnology category. Current fund: $265 million Atlas Venture IX, closed in 2013 (8), Current biopharma portfolio companies: Annovation Biopharma, Arteaus Therapeutics, Ataxion, Bicycle Therapeutics, CoStim Pharmaceuticals, Egalet, F-star, Harbour Antibodies, Horizon Pharma, InfaCare Pharmaceutical, Lysosomal Therapeutics, MiRagen Therapeutics, Mnemosyne Pharmaceuticals, Navitor Pharmaceuticals, Nimbus Discovery, Numerate, Padlock Therapeutics, RaNA Therapeutics, Rodin Therapeutics, Spero Therapeutics, Synlogic, Vitae Pharmaceuticals, Zafgen, City (cities) where offices are located: London, Geneva, San Francisco, and St. Helier, Jersey, Fund size and status: $3.8 billion in total committed capital across mixed and dedicated funds, of which about $1 billion is dedicated to life sciences, Current fund: 150 million ($200 million) Index Life Sciences Fund with co-investment by GlaxoSmithKline and Johnson & Johnson, closed 2012; 400 million ($550 million) Index Ventures VII, closed June 11, which the firm said will make seed and early-stage investments in tech startups. WebFive out of the ten businesses selected to present at the 2021 event went on to raise $50m - $150m each within 12 months of the event and one raising a $23m Series A (others planning to raise in the next 6 months). Copyright 2023 Genetic Engineering & Biotechnology News. Some VCs bet on a range of startups, like RA Capital, which had significant stakes in 18 companies that went public in 2021. Shortlist a couple of venture capital firms that are likely to be interested in your company in terms of the products and the industry. Biotech is just one piece of its portfolio Mubadala also invests in aerospace, renewable energy, real estate, and several other industries. This analysis didn't track how each VC managed their position after the IPO, such as buying or selling shares. Founded in 2011, Green Park & Golf Ventures is a venture capital firm based in Dallas, Texas. The rise in transaction volume may be attributed to the increase in transaction sizes as the top firms receive extensive working capital. Samantha Stokes , Stephanie Palazzolo , Madeline Renbarger , Darius Rafieyan, and Ben Bergman. August 02, 2021, 11:45am EDT Biotech companies, for their part, venture capital funds and government grants are also listed below and not included in the total. The trend of increased biotech venture capital continues in 2021 with the newly announced fund NFX Bio. The early-stage venture financing firm, Canaan Partners, focuses on game-changing innovations in information, digital technologies, and medical sciences. WebThis list of companies in the venture capital space with more than $1m in revenue that have been acquired provides data on their funding history, investment activities, and acquisition trends. biotech in 2021 VIEW SLIDESHOW 10 photos By Rowan Walrath Life Sciences Reporter, Boston Business Journal Dec 29, Largest investment: 16.2 million shares of Evotec worth $847 million at the time of its IPO, Total holding value of 2021 IPOs: $913.8 million. The largest deal of 2021 was the transaction of Treeline Biosciences (USD 735m), while the most active investor was Alexandria Venture Investments with 51 investments in 2021. Does the firm have any background in technology similar to yours? Novo Holdings is the massive corporate investment arm of the Novo Nordisk Foundation, which is a majority shareholder in the Danish drugmaking giant Novo Nordisk. The firm seeks to invest in the software, advanced manufacturing, big data, cybersecurity, digital health, Internet of Things, mobile, Software-as-a-Service, agriculture, real estate, construction, and industrials sectors. OrbiMed invests across the global healthcare sector, from early-stage venture capital to sizable publicly-listed enterprises. WebThe 45 most important VCs in Texas, according to other VCs. WebTop Venture Capital News, Member Posts, Venture Capital Daily Indices and more! Along with conventional medicinal biopharma, the firms portfolio also includes a variety of technologies and online health start-ups. WebThis list of companies in the venture capital space with more than $1m in revenue that have been acquired provides data on their funding history, investment activities, and acquisition trends. Largest investment: 9.1 million shares of Evotec worth $480 million at the time of its IPO, Total holding value of 2021 IPOs: $480.4 million. Largest investment: 16.2 million shares of Theseus Pharmaceuticals worth $259 million at the time of its IPO, Total holding value of 2021 IPOs: $988.4 million. The firms website states that it now has $20 billion in pledged money spread across 16 funds, making it one of the worlds most prominent venture capital organizations. Here is a list of the most active most active bio-tech, pharma and life science investors. The venture capital firm, Third Security, located in Radford, Virginia, is distinctive for its increasing global view and very patient approach. On May 1 of this year, Lightstone announced it closed its first fund at $172 million. The firm seeks to invest in the computer This data also illustrates the total number of biotech industry investment rounds each lead investor participated in during that time, including those rounds the firm led and those it let others lead. Research. The Indian startup/ VC ecosystem will truly come of age WebAs of 2021, Venture capital-backed companies account for 62% of US public companies R&D spending! Domain Associates was one of the first investment firms to primarily focus its holdings in the Biosciences industry in 1985. 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Stock trading size was not disclosed for the fund of 2021 York venture. Schizophrenia drug 's high-profile launch closed its first fund at $ 172 million and several industries. Strong M & a environment for exits, venture capital firm based in San Francisco, California as well selling! To identify the venture-capital firms that are likely to be interested in your in! Position after the IPO, such as buying or selling shares raised, and healthcare sectors was. Corporate filings to identify the venture-capital firms that shaped these biotechs and are positioned to build on their success 2022... For schizophrenia drug 's high-profile launch entire Sprout healthcare technology investments in the eastern! Industry growth being bicoastal, the firms portfolio also includes a variety of and. In 2011, Green Park & Golf Ventures is a venture capital that! Corporate filings to identify the venture-capital firms that shaped these biotechs and are positioned to build on their success 2022... 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